Second-generation anticoagulants (dipha-cinone, difethialone, chlorophacinone, brodifacoum): 4 weeks.Short-acting anticoagulants (warfarin and pindone): 14 days.Dose: Vitamin K 1 should be administered at 3 to 5 mg/kg PO divided Q 12 H with a fatty meal to enhance absorption.Monitor PT and only administer vitamin K 1 if PT becomes elevated (see How Vitamin K 1 Works).Begin prophylactic vitamin K 1 therapy or. Treatment & MonitoringĪfter deciding if decontamination is warranted, the clinician must then choose to either: If emesis is unsuccessful or contraindicated by underlying conditions, such as severely brachycephalic patients and those with seizure disorders or significant cardiovascular disease, the clinician may instead give one dose of activated charcoal with a cathartic.įor patients presented over 8 hours after ingestion, emesis or activated charcoal is unlikely to be effective.
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